Combination Vaccines
Combination vaccines began to appear on the market in 2003, with the introduction of PEDIARIX. The first 5-in-1 vaccine was developed because parents were becoming wary of giving their tiny children five shots on one "well visit." Pediarix is a combination of DTaP + Hepatitis B + polio, injecting seven vaccine antigens but using only one shot, one syringe.
Since that time, many combination vaccines have been developed. Most are used in developing countries to decrease the amount of biological waste (plastic syringes and needles) and healthcare workers can tell unsuspecting parents their infant is getting "protected from several infections by getting just this one shot." However, the side effect profiles of the combination vaccines are extensive. We are gathering the information here for your convenience.
Common combination vaccines for children
| Vaccine Name | Combines | Protection from</thead> |
|---|---|---|
| Pediarix | DTaP + Hep B + IPV | 5 diseases (Diphtheria, tetanus, pertussis, hepatitis B, and polio) |
| ProQuad | MMR + varicella (chickenpox) | 4 diseases (measles, mumps, rubella, and varicella) |
| Kinrix | DTaP + IPV | 4 diseases (Diphtheria, tetanus, pertussis, and polio) |
| Pentacel | DTaP + IPV + Hib | 5 diseases (Diphtheria, tetanus, pertussis, hepatitis B, polio, and Hib (Haemophilus influenzae type b)) |
Kinrix
KINRIX Active immunization against diphtheria, tetanus, pertussis, and poliomyelitis as the fifth dose in the diphtheria, tetanus, and acellular pertussis (DTaP) vaccine series and the fourth dose in the inactivated poliovirus vaccine (IPV) series in children 4 through 6 years of age whose previous DTaP vaccine doses have been... READ MORE
TWINRIX – HEP A + HEP B
TwinRix TwinRix Package Insert VAERS Database for HepB+HepA November 6, 2019 Approval Letter – KINRIX Approval History, Letters, Reviews, and Related Documents – KINRIX Supporting Documents older than three years – KINRIX November 28, 2019 – Aluminum granuloma in a child secondary to DTaP‐IPV vaccination: A case report... READ MORE